The unknown device, descriptor request failed, error code 43.For instance, if your USB ports are dead, if there are partition issues on your external drive, if you have been using the wrong file system, or if there are driver issues in Windows, a USB drive won't show up. There may be a problems with your computer hardware or with Windows itself which may cause a flash drive not detected an error.
However, this is only the worst-case scenario. When users face problems with USB drive not showing up, most people believe that their drive is dead. There can be many reasons why Windows did not detect your flash drive. Part 1: Why Windows Won't Recognize USB Device? Extra Tips: How to Recover Data After Fixing a USB Flash Drive Not Working Error?.Part 2: How Do I Fix USB Flash Drive not Recognized?.